To know how the immune system responds to hepatitis B virus by removing the virus through plasmapheresis.
Age 21 – 70 years old
Hepatitis B carrier ≥ 6 months
On any NA treatment (Lamivudine, Adefovir, Entecavir or Tenofovir) for ≥ 1 year
HBV DNA undetected at screening
No history of depression or psychiatric disease, autoimmune disease & cancer
All of the blood tests and other assessments that are part of this research study will be provided free of charge. To reimburse for your time and inconvenience, you will be paid SGD400 for each plasmapheresis procedure you complete and SGD50 for each study visit.